The plasma care ® is a handy and convinient mobile medical device for the treatment of infected, acute and chronic wounds. It uses cold atmospheric plasma to inactivate microorganisms including multi-resistant pathogens ; CAP stimulates and accelerates wound closure and healing.
Inactivation of bacteria including MRE
Plasma induced physical and chemical processes effecting tiny pores in cell membranes and the reactive plasma species invade the cells. In bacteria, as well as multi-resistant pathogens, the cell structures including the exposed DNS will be destroyed, which inactivates the microorganisms. Antibiotic and other resistances play no role here.
Wound healing can be stimulated
The cell nucleus and cellular repair mechanisms protect human cells against this destructive effect. In vitro it has been observed that the oxidative stress caused by the cold plasma stimulates cell biological survival mechanisms. This is one possible explanation for the improved wound healing observed in some patients.
Example 1 – Postoperative Wound Healing Disorder
patient (63 years old), traumatic lower leg amputation on the left, postoperative wound healing disorder on the residual limb (contact surface of the prosthesis) following a flap surgery, the wound has existed for over 1½ years. No infection.
- 9 treatments (1 min / 13 cm²) carried out within three and a half weeks.
- Reduction of the wound size from 2.04 cm x 1.87 cm to 0.48 cm x 0.51 cm.
Example 2 – Diabetic Foot Syndrome (DFS)
patient (50 years old, type II diabetes mellitus), diabetic foot syndrome; Border zone amputation of the 4th toe on the left. Wound infection with partially resistant Coryne bacteria, enterococci and staphylococci.
- 2 treatments / week in the first 3 weeks, then every 2-4 weeks (9 treatments in 12 weeks) as part of the dressing change in the clinic
- Healing within 12 weeks of starting plasma therapy
Example 3 – Postoperative Wound Healing Disorder
40-year-old male patient: Surgical removal of a sternal liposarcoma with partial resection of the ribs C2-5 on the right and C2-4 on the left. Postoperative wound healing disorder with sternal putrid wound abscess cavity, no improvement after wound revision and application of a wound sealing system, formation of necrotic tissue.
- Treatment over 13 weeks, an average of 3 treatments / week
- During the course of treatment, the crusts and necroses were regularly removed, necrotic sites visibly became smaller, the wound became flatter and closed from below and from the edge
According to the German Medical Technology Association, around 2.7 million people in Germany suffer from complex wounds, and around 900,000 patients suffer from chronic wounds. The wounds don’t close on their own. Therapy with cold plasma offers new hope for wound care. Hundreds of thousands of patients can significantly shorten their hospital stay in this way.
Hospital infections affect 400,000 to 600,000 patients each year
According to the Robert Koch Institute, 400,000 to 600,000 patients in Germany are newly infected with hospital germs every year – and 10,000 to 20,000 die as a result, as a current estimate shows. The researchers cite the larger number of inpatients and hospital beds as the main reasons for this. Germany has the highest number of hospital beds in Europe and the second highest number of hospital patients per 1,000 inhabitants per year. „A reduction in avoidable hospital stays, together with effective infection control and prevention, is therefore an important step in reducing the burden of disease,“ said RKI President Lothar Wieler.
Innovations in medical technology are now possible! Whether in room air purification, in wound treatment or in intensive medicine – cold plasma is revolutionizing medical technology.
Advantages of the plasma care
This is how cold plasma acts on bacteria
Cold plasma consists of partially ionized gas, which makes the cell membrane porous for a few microseconds, so that intercellular structures including the DNA can be destroyed. In contrast to this, human eukaryotic cells are significantly better protected, among other things, by the DNA located in a cell nucleus and, according to previous knowledge, are therefore not damaged by treatment with the plasma care®. The patient is not exposed to radiation, nor does electricity flow through the skin.
This is how cold plasma acts on human cells
Human cells are protected against the action of the plasma due to the cell nucleus and the cellular repair mechanisms. In vitro it was also observed that the oxidative stress caused by the cold plasma stimulates cell biological survival mechanisms. This is one possible explanation for the improved wound healing observed in some patients.